Several studies show that metformin can increase plasma active GLP-1 level through enhancing GLP-1 secretion from intestinal L cells 21 or inhibiting dipeptidyl peptidase 4-mediated GLP-1 degradation 22,23
It remains to be determined whether stimulation of intestinal BTRs has the capacity to reduce energy intake and, hence, body weight in obese individuals
However, he recommends referring to the manufacturers instructions, as some brands may have shorter or longer storage times
The effect of (l-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials.
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Lin X, Zhang Q, Li Q, Deng J, Shen S, Tang M