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MNP exposure has been associated with endothelial dysfunction through increased oxidative stress and impaired nitric oxide (NO) bioavailability [72,73,74]
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The PRAC reviewed data from nonclinical studies, clinical trials, postmarketing surveillance databases, and the medical literature, finding that in large epidemiological studies of adults with type 2 diabetes, semaglutide users had about double the risk of the eye condition compared with nonusers
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