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doi: 10.1016/j.trsl.2016.10.002 116
There is a separate type of steatosis by which phospholipid accumulation leads to a pattern similar to the diseases with inherited phospholipid metabolism defects (e.g., TaySachs disease) Causes: (a) Microvesicular: Aspirin (Reye's syndrome), ketoprofen, tetracycline (especially if expired) (b) Macrovesicular: Acetaminophen, methotrexate (c) Phospholipidosis: Amiodarone, total parenteral nutrition (d) Antiviral: nucleoside analogues (e) Corticosteroid (f) Hormonal: Tamoxifen Granuloma [edit] Drug-induced hepatic granulomas are usually associated with granulomas in other tissues and patients typically have features of systemic vasculitis and hypersensitivity
In contrast, quinoline and artemisinin-based antimalarial drugs showed strong effects on the parasites' E GSH after longer incubation times (24 h)
Heidi Seage is affiliated with Pernicious Anemia Society (Research Group Member)
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