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Ethics declarations Competing interests KGW and VJNB are co-founders and shareholders of Aprea Therapeutics AB, a company that develops novel p53-based cancer therapy

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It is crucial to explicitly note that the evidence presented herein remains overwhelmingly confined to preclinical models

In addition, blockade of IL-36 by IL-36 receptor antagonist reduces CCL20 levels in mouse liver, but increases tissue damage parameters, thus exacerbating AILI [184]

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