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Biochemical pharmacology , 79 (7), 1000-1006

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Common gastrointestinal side effects: The most frequently reported adverse effects are gastrointestinal in nature, occurring in up to 40-80% of patients with higher doses, particularly during dose escalation: [13] [14] Nausea (most common, typically improves after 4-8 weeks) Vomiting Diarrhoea or constipation Abdominal discomfort or bloating Reduced appetite These effects can be minimised by starting with low doses and gradually titrating upwards according to manufacturer guidance

On the 8th day, they performed a short 4KM time trial

It may accelerate wound closure, reduce scar formation, and support the formation of normal tissue architecture

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