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CrossRef The role of the resveratrol-sirtuin axis in the treatment of metabolic dysfunction-associated diseases Jiale Yang, Shuping Chen, Tiantian Zeng, Yuxuan Zhang, Zhaoxin Li, Haifang Li Exploration of Endocrine and Metabolic Diseases .2026;[Epub] CrossRef GLP-1 receptor agonistSGLT-2 inhibitor combination and risk of major adverse liver and cardiovascular outcomes in adults with MASLD and type 2 diabetes Xianhua Mao, Hong Fan, Man-Fung Yuen, Ramsey Cheung, Wai-Kay Seto, Mindie H

Frequency: Administer one subcutaneous injection daily for the duration of the study

If GI side effects are intolerable during any escalation step and the patient is on concurrent opioids, extend the current dose plateau by 2 to 4 additional weeks before escalating

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and Abe, Y., 2002