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Inhibitors of copper chaperones address the concern of other copper chelators in that they non-selectively bind other metal cations and produce toxic side effects (11)

The 2025 IV safety study tolerated doses up to 20 mg IV in two healthy volunteers without adverse events the highest-quality published human safety data

Consistent daily use is recommended for best results

4.1.2 Occupational exposure studies Workplace exposure investigations provide particularly valuable insights into EED toxicity due to higher exposure levels and better-controlled exposure assessment protocols

Diagnosis (11,13) The clinical suspicion is confirmed by serial radiological studies (Table III)