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Why have GLP-1 receptors historically been difficult to target with small molecules, and what has changed to make oral versions possible now
All procedures were carried out strictly in accordance with the manufacturers instructions
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Some food for thought: Clothes & retailers After starting GLP1s, people are purchasing: More: Athleisure, apparel, footwear, casual attire, and intimates/lingerie Less: Plus-size retailers, luxury apparel and accessories, business casual So what happens to companies in the more bucket like Lululemon, Nike, Victoria Secret
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Among the main mechanisms of this multidrug resistance is the overexpression of ATP-binding cassette (ABC) transporters that mediate drug efflux, and, specifically, ABCB1, ABCG2 and ABCC1 are known to cause cancer chemoresistance
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