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Lenzi A, Picardo M, Gandini L, et al
Simultaneously, Akt activation suppresses the ubiquitin proteasome system through inhibition of FoxO-mediated transcription of E3 ubiquitin ligases (MAFbx/Atrogin-1, MuRF1), which are responsible for protein degradation
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These effects can translate into greater endurance, less post-workout soreness, and improved overall performance
The data are limited at this time, but case reports show that people taking GLP-1 meds reported increased energy, reduced pain, and reduced fatigue
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