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To understand why weight loss medicines may be associated with hair shedding, it helps to understand the normal hair growth cycle

The addition of the C20 fatty diacid moiety facilitates binding to albumin in the bloodstream, which prolongs the drug's half-life to approximately five days and permits once-weekly administration, as documented in the product's Summary of Product Characteristics (SmPC)

GI side effects during transition are typically milder than the jump from 2.5 to 5 mg because the body has already adapted to the medication's mechanism

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