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To qualify, these women also had to be involved in a current stable, monogamous relationship lasting a minimum of six months, with a commitment to be sexually active at least once monthly

doi: 10.1016/0190-9622(90)70333-D [5] Lim VM, Do A, Berger TG et al

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Dehydration can make it harder for the technician to find a vein and can also cause some markers, like kidney function, to look artificially strained

But again, in the absence of clinical trials, we still don't know if and how they are working in humans