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Growth hormone is vital for maintaining lean muscle mass, burning fat, and supporting metabolism, particularly as men age

An example is the microtubule binding protein stathmin-2 (STMN2), which exhibits reduced expression due to TDP-43 mislocalization [202] and is currently being targeted by an antisense oligonucleotide in clinical trial

That is the strongest class of evidence there is for a side effect: measured in randomized, controlled approval trials

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