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10.1152/ajplung.00287.2007 Am
According to this study, roughly half the population has a subclinical deficiency, and claims that the majority are at risk
This means they're involved in regulating a host of other functions: Appetite and Energy Homeostasis (MC3R & MC4R): These receptors in the brain are critical for controlling food intake and energy expenditure
The review confirmed that TB4 is released by platelets, macrophages, and many other cell types following injury, where it protects cells and tissues from further damage and reduces apoptosis, inflammation, and microbial growth
That longer activity is what makes it attractive in performance, recovery, and increasingly, in aesthetic settings
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