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PQQ can be reduced by various substances and converted back to its oxidized state by oxygen

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Instead of returning to a resting state after the initial infection clears, these cells continuously release inflammatory cytokines, such as IL-6 and TNF-alpha

Its core action mechanism involves multi-target regulation, including inhibiting central nervous excitability, regulating calcium ion channels, inhibiting the release of inflammatory factors, and directly relaxing smooth muscles

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MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition