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Geriatric use: Elderly patients may be more sensitive to NSAIDs, so it is recommended to use the lowest effective dose

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If you have neurological symptoms (pins and needles, numbness, balance issues), severe fatigue, unexplained weight loss, chest pain, breathlessness, or symptoms that are worsening, you should seek medical assessment promptly.

The PICOs elements were defined as follows: P (Participants): subjects of any age diagnosed with Vitamin B12 deficiency