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The perception of electrophilic / oxidative stress in acinar cells as the obligate intermediate phenotype in the pathogenesis of chronic pancreatitis (Figure 1) fulfils a set of postulates derived from Kochs classical work on tuberculosis, as modified for a polygenic disease (23,24)

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As the weight came off, some felt more motivated to exercise, more at ease being seen in public, more able to build routines that had long felt out of reach

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