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NICE guidance on type 2 diabetes management (NG28) supports an individualised approach to minimising hypoglycaemia risk, including reviewing medication regimens when clinically significant changes in diet, weight, or glycaemic control occur

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Increasing fluid intake, consuming fiber-rich foods, and taking over-the-counter anti-diarrheal or laxative medications as needed can help manage these symptoms

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Glycemic control generally deteriorates progressively after tirzepatide cessation, with HbA1c levels moving toward pre-treatment values without alternative therapy

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