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The Nrf2 pathway responds to ROS by activating the transcription of phase II detoxification enzymes

From a mechanistic standpoint, factors that induce ferroptosis can exert direct or indirect effects on the phospholipid hydroperoxidase, glutathione peroxidase 4 (GPX4), via multiple pathways

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[82] used a simple and mildly ionic gelation method to make a kind of nano particle composed of -PGA and chitosan, which can effectively reduce blood glucose level by loading insulin