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The authors conclude that this antioxidant-based support is well tolerated and may provide clinically meaningful benefits, although controlled trials are needed to confirm efficacy ( Weight of evidence: Overall evidence is Low : primarily preclinical with heterogeneous designs and no consistent human biomarkers

Although methylcobalamin and vitamin B12 are terms used interchangeably, vitamin B12 is also available as hydroxocobalamin, a less commonly prescribed drug product (see Hydroxocobalamin monograph), and methylcobalamin

Importantly, these expanded HBs retained bipotency, co-expressing both hepatic and early cholangiocyte markers [1]

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