Kelliher JM, Mirzayi C, Bordenstein SR, Oliver A, Kellogg CA, Hatcher EL, et al
Importantly, semaglutide carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
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This is comparable to the weight loss benefits of Wegovy, the injectable version of semaglutide
Indeed, chronic slight hyperinsulinemia is a pro-oxidant factor