Weight reduction has been linked to improved CV risk factors and complications, particularly hypertension, ASCVD, HF, AF, pulmonary hypertension, and left ventricular hypertrophy ( 3.2 Effects on hypertension and hyperlipidemia Besides their contribution to weight reduction and glycemic control, GLP-RAs were associated with BP and lipid levels reduction ( Effects on lipid profile were collected as secondary outcomes from several clinical trials
Nonetheless, multiple sources of bias likely influenced results, including exposure misclassification (es., current shift status used as proxy for lifetime exposure), survivor bias and left truncation in cohorts, and incomplete control for reproductive or behavioral confounders 276
Pimenta W, Korytkowski M, Mitrakou A, et al
Have you had a homocysteine blood test and a methylmalonic acid - MMA - that would show whether you were low at cellular level
And not in a good way
Some protocols incorporate topical application to specific areas of concern alongside injectable administration for localized plus systemic benefits