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Severe deficiency can contribute to fatty liver changes, which is one reason choline gets framed as liver support. Details are summarized in the NIH ODS Choline fact sheet for health professionals
Patients on lipotropic protocols are simultaneously dieting, exercising, and being weighed by a clinician every few weeks
This is the window that the Finkley 2005 trial captured, and the Carey/Pickart ultrasound work confirmed at the structural level: an average 28% increase in collagen density, with top responders at 51%
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MIC contains Methionine, Inositol and Choline