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Part of the reason is that, while some studies showed strong effects in controlled settings, the evidence was limited (small sample sizes, shortterm)

Enhancement of impaired olfactory neural activation and cognitive capacity by liraglutide, but not dapagliflozin or acarbose, in patients with type 2 diabetes: A 16-week randomized parallel comparative study

Functional metabolic effects

How much and what type of weight training is required to offset this downside

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The ones waiting for the trend to become undeniable are ceding that window, and Circanas analysis adds a further layer of urgency: the categories with the steepest GLP-1 spending declines are often the same categories with the most bloated SKU counts, the result of years of incremental product extensions that made sense when volume was growing but become expensive to maintain as demand contracts