Three tissues/organs are affected in PCD: cardiac muscle which leads to progressive cardiomyopathy
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Results and discussion Peptide-oligourea hybrids design and functional assay Our peptideoligourea hybrids design started with GLP-1-NH 2 and the introduction of a glycine in position 2 of GLP-1 instead of alanine (GLP-1-G 2 , 1 ) as it is known to prevent DPP-4 degradation 31,32,33
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Differences in proteins associated with islet survival and beta cell integrity In agreement with the observations from the cross-sectional serum proteomics study of Zhi and co-workers [5], TGF--induced protein ig-h3 (TGFBI) was less abundant in the individuals with type 1 diabetes
& Clegg, D