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There is ample documentation indicating that endothelial dysfunction, which is a response to cardiovascular risk factors, typically precedes the development of atherosclerosis (54)

Serious (seek medical attention immediately): Severe hypotension, exacerbation of angina on initiation (rare), gingival hyperplasia with long-term use

International Journal of Endocrinology, 2018 , 4847376

This is especially true for those who struggle with diet and exercise alone

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