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Patients on higher maintenance doses or those with reduced kidney clearance may experience more noticeable effects from dosing-interval changes than those early in titration
In 1996, it was reported that intracerebroventricular (ICV) of GLP-1 reduced food intake in fasted rats in a dose-dependent (53), suggesting that GLP-1 may act on central GLP-1R to produce satiation
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Hair loss concerns have emerged in community discussions, though clinical trial data did not identify this as a statistically significant adverse event
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