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58 Interestingly, the expression of this enzyme does not fulfill an instantaneous snapshot of the blood toxicity, but an average value over a time span of about 2/3 months (corresponding to the mean life of the erythrocyte) as it is exclusively expressed during erythropoiesis
To date, no study has pharmacologically targeted the ferroptosis pathway in PTC by RSL3-mediated suppression of GPX4 activity
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