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These observations were corroborated by single-cell calcium imaging studies in slices of arcuate nuclei, demonstrating that GLP-1MK-801 inhibits the NMDA-induced intracellular calcium surge relative to GLP-1 alone (Extended Data Fig

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Diabetes Care 32(5):762768 Buse JB, Henry RR, Han J, Kim DD, Fineman MS, Baron AD et al (2004) Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes

Novo Nordisk (Denmark): Novo, as described above, dominates the GLP-1 market with products like Wegovy and Ozempic

Several clinical trials are currently investigating whether GLP-1 receptor agonists can slow cognitive decline or reduce Alzheimer's disease risk