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10.1016/S0969-8051(00)00180-3 Nucl
Aib2 (-amino isobutyric acid) residues at positions 2 and 20 provide stability against Dipeptidyl Peptidase 4 (DPP4) cleavage and contribute to GIP activity
Moreover, AS-IV has been shown to mitigate obesity-related hypertension by repressing inflammatory responses and enhancing leptin resistance, likely through upregulation of 7nAchR levels and inhibition of IKK/NF-B signaling in the hypothalamus and adipose tissue ( Given the strong link between obesity and arrhythmia, the aforementioned studies suggest that astragaloside may reduce the likelihood of arrhythmia by regulating fat metabolism
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GLP-1 4