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Dose reduction strategies After maintaining goal weight for 6 to 12 months at a given dose, some individuals successfully transition to lower maintenance doses

The core regulatory axes of ferroptosis primarily involve redox balance, lipid metabolism, iron regulation, and mitochondrial function ( Accumulating evidence indicates that ferroptosis critically contributes to the progression of diabetes and its complications via mechanisms involving lipid peroxidation and inflammation-activated neovascularization ( 2 Molecular mechanisms of ferroptosis: core regulatory pathways 2.1 Regulatory association between iron metabolism imbalance and ferroptosis Iron, an essential element for living organisms, serves as a crucial trace element in numerous biochemical reactions and plays a central role in fundamental physiological processes such as DNA synthesis, oxygen transport, and cellular energy production

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2021;12:630032 Pan SY, Tian HM, Zhu Y, Gu WJ, Zou H, Wu XQ, et al