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Discontinuation was common: 54.2% of the patients in the study data discontinued their GLP-1 RA (30 days without medication on hand), highlighting the need for additional research on the role of shortages, adverse events, and costs

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Histologically, congenital hyperinsulinism can be diffuse, where all beta cells are affected, or focal, where there is a focal area of adenomatosis ( Plasma incretin concentrations in both the fasting and fed state have been measured in patients with different forms of congenital hyperinsulinism

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