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Further subgroup analyses based on the dosage and duration of treatment also demonstrated no significant SMD in any subgroups (Supplementary Figure 1)
Duerrschmid C, He Y, Wang C, Li C, Bournat JC, Romere C, et al
Notably, in the condition of excess hemin exposure and hypoxia, our findings suggest an important contribution of the TSS pathway and its regulation by DMF for de novo cysteine synthesis and GSH generation in protecting against the oxidative and ferroptotic stresses in SCD erythroblasts
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