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In another paclitaxel-induced peripheral neuropathy (PIPN), 4-PSQ was observed to decrease paclitaxel-induced mechanical and thermal hypersensitivity, possibly related to modulation of oxidative stress in the spinal cord, hippocampus, and cerebral cortex of PIPN mice [163]
Moreover, peroxisomes, organelles involved in lipid metabolism, contain enzymes such as acyl-CoA oxidase that generate hydrogen peroxide as a by-product [61]
Identity and concentration are verified so vial 900 matches vial 1
We used the model to study the extent of liver damage caused by overdoses or by chronic use of therapeutic doses, and the effects of polymorphisms in glucoronidation enzymes