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doi: 10.3389/fimmu.2025.1728091 37 LiuZWenJHuFWangJHuCZhangW

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Most ingredients used in GLP-1 patches: Have been studied primarily in oral supplement form Are not proven to be absorbed through the skin in effective amounts Lack robust human trials using transdermal delivery This doesn't mean the ingredients themselves are ineffective

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Additional benefits have been observed in renal outcomes , with some GLP-1 agonists showing protective effects, primarily through reductions in albuminuria and a slower decline in estimated glomerular filtration rate (eGFR)

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