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Ursodeoxycholic acid, a bile acid that reduces cholesterol saturation, has been studied for gallstone prevention during rapid weight loss, but is not routinely recommended

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Any future use would require appropriate medical assessment, ongoing monitoring and a personalised approach based on individual health needs

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They underscore not only the clinical impact of this drug class but also the urgent need to comprehensively review the evolving evidence base, clarify mechanistic insights, and explore future directions in both metabolic and non-metabolic disease contexts