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Growth and apoptosis Ex-4 significantly improves the survival of rat cortical neurons under oxygen/glucose deprivation (OGD) conditions through reduced apoptosis rates, increased expression of glucose-regulated protein 78, and decreased levels of C/EBP-homologous protein, indicating the role of Ex-4 in modulating unfolded protein response for protecting neurons from ischemic damage [56]

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Rodriguez, conducted a cohort study involving 125,474 patients who started GLP-1 medications, including Victoza (liraglutide), Ozempic and Wegovy, and Mounjaro and Zepbound between January 1, 2018 and December 31, 2023

This means that most of it is broken down before it reaches the digestive system