Because this is a recently recognized adverse effect, treatment strategies are drawn from case report outcomes, general allodynia management guidelines, and clinical experience with neuropathic pain
Its primary role is to neutralize free radicals, protect cells from oxidative stress, and support the immune system
At six months, 54% of patients achieved a 1-point reduction in HS-PGA, while 12% achieved a 2-point reduction
Key studies include: Weight regain and cardiometabolic effects after withdrawal of semaglutide (STEP-1 trial extension): This study found that participants regained about two-thirds of the weight they had lost within one year after stopping semaglutide
But based on similar GLP-1s , it will likely have some safety warnings related to conditions like pancreatitis and gallbladder problems
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