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Retatrutide binds three receptors: the GLP-1 receptor (regulates appetite, insulin secretion, and gastric emptying), the GIP receptor (influences insulin response and adipose handling), and the glucagon receptor (affects energy expenditure and hepatic lipid handling)
10.1067/mpd.2001.114480 3
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Unknown long-term effects of altered pharmacokinetics No one knows the long-term safety profile of microdosed retatrutide because no one has studied it
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