It is a hormone the body naturally produces in response to eating
It is particularly important not to discontinue semaglutide without medical guidance, as abrupt cessation may lead to deterioration in glycemic control or weight regain
We dont have much data yet, but one study from late in 2025, which compared tirzepatide to both transdermal (through the skin) testosterone and placebo, made an argument worth considering: Authors La Vignera & colleagues argued that tirzepatide may be effective in improving both metabolic parameters, ED, and gonadal hormone levels in patients with obesity and metabolic hypogonadism, also known as low testosterone levels
Oral weight loss medications might be appropriate and are often a good alternative for those who prefer injection-free options
Jillian Gilchrest, D-West Hartford, said of the proposal
When comparing Wegovy injection vs oral alternatives, the injection remains the primary option for weight management due to its higher clinical effectiveness and FDA approval for obesity treatment