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The meta-analysis of the PIONEER and SUSTAIN trials stated, diarrhoea or dehydration can lead to the increase in blood viscosity, semaglutide increases the risk of deep vein thrombosis possibly due to increasing that of diarrhoea. Similarly, the authors said more research is needed on whether the weight loss often experienced while taking semaglutide drugs may increase the risk of DVT, stating, Moreover, whether an increase in deep vein thrombosis is related to a decrease in body weight also needs to be further investigated. People who are taking Ozempic may have patient-specific risk factors that increase the likelihood of developing blood clots

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doi: 10.5607/en.2017.26.4.227 133 BjotYGiroudM

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Moreover, excessive alcohol intake can lead to a depletion of glutathione levels, resulting in an imbalance between reactive oxygen species and antioxidants, increasing oxidative stress, and causing damage to the liver