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Those prescribed non-GLP-1 diabetes medications (e.g., insulin, metformin)

They share the same three primary receptor targets: GLP-1 GIP Glucagon Because of this shared mechanism, both compounds are part of the broader movement toward multi-agonist incretin drugs designed to influence several metabolic hormone systems simultaneously

& Schleicher, E

It's unclear in the short term what legal authority the administration would have to enforce the order

Injectable semaglutide reduces A1c by approximately 1.5 to 2.0 percentage points on average, while oral formulations reduce A1c by approximately 1.0 to 1.5 percentage points