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Explore the full application note: #Biopharma #LCMS #DrugDiscovery #Tirzepatide #GLP1 #Agilent To view or add a comment, sign in I am very excited to share this terrific news with you: the FDA has given a safe to proceed decision of our IND for the Inflam Motion trial, a phase 2 proof of concept clinical trial comparing 4P004, intraarticular liraglutide, with placebo in people suffering from knee OA with synovitis

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Variants in FTO (the fat-mass and obesity-associated gene), GLP1R (the GLP-1 receptor gene, the direct target of every GLP-1 compound), MC4R (a melanocortin receptor central to satiety), and TCF7L2 (a transcription factor tied to glucose homeostasis) describe the terrain any compound acts on

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This is vital for individuals with conditions like atrial fibrillation, deep vein thrombosis (DVT), or those who have had heart valve replacements