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After approximately five half-lives, a medication is considered largely eliminated from the body
The concern isnt just that youll develop antibodies against the peptide itselfits that those antibodies might cross-react with your own endogenous proteins
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Pharmacotherapy for Obesity: recent updates
The intranasal spray formulation provides additional scientific value by allowing laboratories to investigate formulation stability, spray consistency, peptide integrity, physicochemical characteristics, analytical reproducibility, and intranasal delivery system performance
doi: 10.1038/nri2992 49 DenkersEYButcherBADel RioLKimL
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