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"I do want to lose weight," Metz concedes
10.1038/nn.4025 Summary Keywords Alzheimerrs disease, GLP-1 agonists, estrogens, prevention, metabolism Citation Lizcano F, Sanabria D and Aviles E (2025) Hormonal modulation, mitochondria and Alzheimers prevention: the role of GLP-1 agonists and estrogens
Similar patterns appeared in other obesity-related cancers: Non-small cell lung cancer: progression to Stage IV roughly 10% versus 22% Colorectal cancer: statistically significant reduction in progression Hepatocellular (liver) cancer: signal in the same direction A separate JAMA Oncology study by Dai and colleagues (2025), distinct from the Cleveland Clinic ASCO analysis, found about a 17% lower overall cancer incidence (hazard ratio approximately 0.83) in adults with obesity who used GLP-1 receptor agonists, with most of the signal coming from skin cancers and obesity-related solid tumors
Reading that profile alongside the protocol is the test before you invest approach, turning guesswork into an informed conversation with your provider
Structural basis of omega-3 fatty acid transport across the bloodbrain barrier
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