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In addition, oxidative stress causes cellular stress and inflammation at the cellular level and degeneration of cellular tissue

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Ehsan Rahimy, MD, of Byers Eye Institute, Stanford Medicine, can be reached at [email protected]

Extracts of the medium were incubated at 80 C for at least 15 min before being centrifuged at 15,000 g for 20 min

There was no significant difference in the level of the measured antioxidants at different categories of years of smoking among the group of smokers

Alongside impairments in carbohydrate metabolism, evidence of reduced carnitine levels suggest a dysfunction in mitochondrial -oxidation, leading to accumulation of long-chain fatty acids and elevated markers of lipid elongation and desaturation (Pastural et al., 2009)