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Lee NJ, Nguyen AD, Enriquez RF, Doyle KL, Sainsbury A, Baldock PA, et al
10.1172/JCI116842 22 MarticI.Jansen-DrrP.CavinatoM
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This selectivity means tanning effects are achieved with limited activation of MC3R, MC4R, and MC5R the receptors responsible for off-target effects such as libido modulation (MC4R), appetite suppression (MC4R/MC3R), and sebaceous gland activity (MC5R)