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1a, Al 2 O 3 nanoparticles exerted specific transcriptional effects leading to significantly increased expression of 54 genes and decreased expression of 304 genes, with a cutoff as 2 or more fold change and P 99.8 % purity)
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They usually attach to each other or associate with nearby proteins, such as integrins, to form a tetraspanin membrane domain ( v 6 for prostate cancer ( 6 4 and 6 1 for lung cancer, and v 5 for liver cancer metastasis (Hoshino et al., 2015)
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Structurally, the product was optimized on the basis of exenatide, and the glycine 2, methionine 14 and asparagine 28 positions were modified to improve enzyme stability and chemical stability based on the polypeptide backbone
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