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In particular, Ikonomidis et al

The route of administration can have a profound impact on the localization of the immunity generated [43,44,45]

These can reflect a localized tissue response to the injection

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doi: 10.1016/j.biopha.2020.110218 188 Simental-MendaLESnchez-GarcaALinden-TorresESimental-MendaM

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