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However, it can sometimes cause gastrointestinal side effects such as nausea, vomiting, diarrhea, and constipation, especially when starting treatment or increasing the dose

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Natural human GLP-1 exists primarily as GLP-1(7-36) amide, a peptide that is rapidly degraded by DPP-4, resulting in a half-life of only 2 to 3 minutes

This candidate vaccine is currently under evaluation in phase I clinical trials (Table 1)

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Vegetarians, vegans, and older adults may be more prone to its deficiency