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This dual engagement may explain why BPC-157 appears to promote not just collagen deposition but organised collagen deposition: the FAK-paxillin axis coordinates cytoskeletal tension, and cells under appropriate cytoskeletal tension deposit collagen with directional preference aligned to the local force field

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Ito T, Igarashi H, Pradhan TK, Hou W, Mantey SA, Taylor JE, Murphy WA, Coy DH, Jensen RT

In the unlikely event of significant copper toxicity, treatment involves IV chelation therapy using EDTA, which binds to excess copper and allows it to be excreted through the kidneys

More than 20 products based on ASOs, aptamers, siRNA, and mRNA have been approved for marketing to treat various rare genetic disorders (Table 1)